It depends, do you play mostly casual games or only career mode ? The updated line ups are reflected in casual games, custom tournaments, basically every other mode except for career mode.
@hammadahmed88 suggested that if you really don't want certain player to be picked by their national teams due to retirement in real life or other issues like KP not being selected for England again then you can edit their nationality to some lowly ranked country that you will never come across in the game's career mode.